The Masoretes in the 7th to 11th centuries laid the foundation for grammatical analysis of Hebrew. As early as the 9th century Judah ibn Kuraish discussed the relationship between Arabic and Hebrew. In the 10th century, Aaron ben Moses ben Asher refined the Tiberian vocalization, an extinct pronunciation of the Hebrew Bible.

The first treatises on Hebrew grammar appear in the High Middle Ages, in the context of Midrash (a method of interpreting and studying the Hebrew Bible). The Karaite tradition originated in Abbasid Baghdad around the 7th century. The Diqduq (10th century) is one of the earliest grammatical commentaries on the Hebrew Bible.

Solomon ibn Gabirol in the 11th century composed a versified Hebrew grammar, consisting of 400 verses divided into ten parts. In the 12th century, Ibn Barun compared the Hebrew language with Arabic in the Islamic grammatical tradition. 11th to 12th century grammarians of the Golden age of Jewish culture in Spain included Judah ben David Hayyuj, Jonah ibn Janah, Abraham ibn Ezra, Joseph Kimhi, Moses Kimhi and David Kimhi. Ibn Ezra gives a list of the oldest Hebrew grammarians in the introduction to his Moznayim (1140). Roger Bacon was "a tolerable Hebrew scholar". Profiat Duran published an influential grammar in 1403.

Judah Messer Leon's 1454 grammar is a product of the Italian Renaissance. Hebrew grammars by Christian authors appeared during the Renaissance. Hieronymus Buclidius, a friend of Erasmus, gave more than 20,000 francs to establish a branch of Hebrew studies at Louvain in Flanders. Elijah Levita was called to the chair of Hebrew at the University of Paris. Cardinal Grimani and other dignitaries, both of the state and of the Church, studied Hebrew and the Cabala with Jewish teachers; even the warrior Guido Rangoni attempted the Hebrew language with the aid of Jacob Mantino (1526). Pico de la Mirandola (d. 1494) was the first to collect Hebrew manuscripts, and Reuchlin was the first to write a modern grammar of the Hebrew language (1506). Conrad Gesner (d. 1565) was the first Christian to compile a catalogue of Hebrew books. Paul Fagius and Elia Levita operated the first Hebrew printing office in the 1540s. Levita also compiled the first Hebrew-Yiddish dictionary.

Through the influence of Johannes Buxtorf (d. 1629) a serious attempt was made to understand the post-Biblical literature, and many of the most important works were translated into Latin. Gesenius' Hebrew Grammar appeared in 1813.